SCHEMBL1230233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17082477	0.89	NPC1 (0.44)	TLR2TLR1NPC1RAB9ANLRP3
	SCHEMBL1230291	0.83	SCN5A (0.40)	NPC1RAB9ANLRP3MAP4K4KIF11
	SCHEMBL1259287	0.83	KIF11 (0.51)	TLR2TLR1NPC1RAB9ANLRP3
	SCHEMBL2743492	0.83	KIF11 (0.51)	TLR2TLR1NPC1RAB9ANLRP3
	SCHEMBL1230313	0.83	MAOA (0.43)	NPC1RAB9ANLRP3MAP4K4CA12
	SCHEMBL19244899	0.81	MAP4K4 (0.50)	NPC1RAB9ANLRP3MAP4K4HDAC1
	SCHEMBL4549455	0.81	NPC1 (0.58)	NPC1RAB9ANLRP3MAP4K4PTGS2
	SCHEMBL4549457	0.81	NPC1 (0.67)	NPC1RAB9ANLRP3MAP4K4ALDH1A1
	SCHEMBL1260380	0.80	TLR2 (0.65)	TLR2TLR1NPC1RAB9APTGS2
	SCHEMBL1260302	0.80	KIF11 (0.55)	TLR2TLR1NPC1RAB9ANLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.