Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611365 | 0.88 | ROCK2 (0.44) | KDM4ERECQLRAB9AHDAC6ALDH1A1 | |
| SCHEMBL4550064 | 0.84 | KDM4E (0.46) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2611393 | 0.82 | RAB9A (0.49) | KDM4ERECQLRAB9AHDAC6HDAC8 | |
| SCHEMBL2611274 | 0.79 | HTT (0.51) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2619420 | 0.78 | KDM4E (0.49) | KDM4ERECQLRAB9AHDAC6HDAC8 | |
| SCHEMBL2118827 | 0.77 | RAB9A (0.47) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2611268 | 0.77 | HDAC6 (0.46) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2619265 | 0.75 | KMT2A (0.47) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2115685 | 0.75 | KDM4E (0.52) | KDM4ERECQLRAB9AHDAC6HDAC3 | |
| SCHEMBL2611379 | 0.74 | ROCK2 (0.53) | KDM4ERECQLRAB9AHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |