Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550333 | 0.85 | PTGS2 (0.38) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL2715765 | 0.84 | PTGS2 (0.37) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2714225 | 0.80 | AAK1 (0.38) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4550308 | 0.80 | LOXL2 (0.38) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10290355 | 0.79 | — | — | |
| SCHEMBL4550344 | 0.78 | LOXL2 (0.37) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2716622 | 0.78 | SMN1; SMN2 (0.39) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL2717257 | 0.78 | LOXL2 (0.39) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4550349 | 0.78 | LOXL2 (0.37) | LOXL2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4550332 | 0.78 | LOXL2 (0.37) | LOXL2ALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |