SCHEMBL4550665

SCHEMBL4550665

CCCCCNc1cccc(-c2ccccc2)c1[O]

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 3/20 0.50
SOAT1 P35610 6/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
STAT1 P42224 1/20 0.43
RAB9A P51151 1/20 0.43
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
APAF1 O14727 1/20 0.40
KCNH3 Q9ULD8 1/20 0.40
PDE4B Q07343 1/20 0.40
SOAT2 O75908 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1726143 0.85 SOAT1 (0.55) KCNA3SOAT1L3MBTL1ALDH1A1NPC1
SCHEMBL1926388 0.83 KCNA3 (0.48) KCNA3SOAT1L3MBTL1ALDH1A1NPC1
SCHEMBL12984564 0.80 SOAT1 (0.53) KCNA3SOAT1ALDH1A1APAF1KDM4E
SCHEMBL9927894 0.79 SOAT1 (0.51) KCNA3SOAT1L3MBTL1ALDH1A1NPC1
SCHEMBL1926387 0.78 L3MBTL1 (0.48) SOAT1L3MBTL1ALDH1A1MAPTCNR1
SCHEMBL1724131 0.76 L3MBTL1 (0.51) SOAT1L3MBTL1ALDH1A1NPC1MAPT
SCHEMBL1580117 0.74 MEN1 (0.45) KCNA3L3MBTL1ALDH1A1NPC1MAPT
SCHEMBL11266453 0.74 L3MBTL1 (0.54) SOAT1L3MBTL1ALDH1A1MAPTCNR1
SCHEMBL8535750 0.74 L3MBTL1 (0.54) SOAT1L3MBTL1ALDH1A1MAPTCNR1
SCHEMBL11266466 0.74 L3MBTL1 (0.54) SOAT1L3MBTL1ALDH1A1MAPTCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534894-B2 Biphenyloxy-acids WYETH (US) 2009-05-19 US disclosed
EP-1667959-A1 BIPHENYLOXY-ACIDS Wyeth (US) 2006-06-14 EP disclosed
US-20060020003-A1 Biphenyloxy-acids WYETH (US) 2006-01-26 US disclosed
WO-2005030702-A1 BIPHENYLOXY-ACIDS WYETH (US) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020003-A1 Biphenyloxy-acids AHR, ARNT, NR1H4 KCNA3 4188/4885SOAT1 1672/4885L3MBTL1 1585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.