Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047968 | 0.86 | ALDH1A1 (0.53) | KMT2AALDH1A1TSHRL3MBTL1POLB | |
| SCHEMBL10063079 | 0.80 | POLB (0.52) | KMT2AALDH1A1TSHRL3MBTL1POLB | |
| SCHEMBL10062603 | 0.79 | USP2 (0.49) | KMT2AALDH1A1POLBMAPK1LMNA | |
| SCHEMBL11889924 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1TSHRL3MBTL1POLB | |
| SCHEMBL17262132 | 0.76 | CCR5 (0.35) | POLB | |
| SCHEMBL3839702 | 0.75 | CCR5 (0.57) | — | |
| SCHEMBL14045658 | 0.74 | KDM4E (0.35) | KMT2AALDH1A1TSHRPOLBMAPK1 | |
| SCHEMBL13088273 | 0.74 | KMT2A (0.56) | KMT2AALDH1A1TSHRL3MBTL1POLB | |
| SCHEMBL4197599 | 0.72 | CCR5 (0.44) | — | |
| SCHEMBL20640318 | 0.72 | CCR5 (0.44) | KMT2AALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |