Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 14/20 | 0.40 |
| ▸ | CHRM5 known ✓ | P08912 | 10/20 | 0.40 |
| ▸ | CHRM3 known ✓ | P20309 | 10/20 | 0.40 |
| ▸ | CHRM4 known ✓ | P08173 | 8/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587256 | 0.97 | CHRM2 (0.41) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL194217 | 0.95 | CHRM2 (0.40) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL28480769 | 0.86 | CHRM2 (0.53) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7943589 | 0.81 | SLC22A1 (0.38) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| Bromide SCHEMBL18260613 | 0.80 | SLC22A1 (0.41) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| SCHEMBL561584 | 0.80 | CHRM2 (0.42) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| SCHEMBL18260614 | 0.80 | CHRM2 (0.35) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7945663 | 0.78 | SLC22A1 (0.42) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14574759 | 0.78 | PRKD3 (0.36) | CHRM2CHRM5CHRM3CHRM4CHRM1 | |
| SCHEMBL5196667 | 0.77 | SLC22A1 (0.43) | CHRM2CHRM5CHRM3CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388705-A1 | WATER-SOLUBLE, BIODEGRADABLE DIHYDROXYALKYL CELLULOSE | ISP INVESTMENTS LLC (US) | 2025-12-25 | — | — | US | claimed |
| EP-4581094-A2 | WATER-SOLUBLE, PARTIALLY BIODEGRADABLE DIHYDROXYALKYL CELLULOSE | ISP Investments LLC (US) | 2025-07-09 | — | — | EP | claimed |
| CN-119998333-A | Water-soluble, partially biodegradable dihydroxyalkyl cellulose | 埃斯普投资有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-116535540-B | Quaternized modified chitin, sponge thereof, preparation method of porous microsphere and application of quaternized modified chitin | 武汉大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117756965-A | Acrylonitrile polymer containing quaternary ammonium salt group and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2024049833-A2 | WATER-SOLUBLE, PARTIALLY BIODEGRADABLE DIHYDROXYALKYL CELLULOSE | ISP INVESTMENTS LLC (US) | 2024-03-07 | — | — | WO | claimed |
| CN-116410345-B | Cationized hyaluronic acid or salt thereof and method for producing same | 华熙生物科技股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-116535540-A | Quaternized modified chitin, sponge thereof, preparation method of porous microsphere and application of quaternized modified chitin | 武汉大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116410345-A | Cationized hyaluronic acid or salt thereof and method for producing same | 华熙生物科技股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-114832626-B | Composite nanofiltration membrane, preparation method and application | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-115672047-A | Anion exchange membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115528284-A | Composite anion exchange membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-110394065-B | Composite nanofiltration membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-114832626-A | Composite nanofiltration membrane, preparation method and application | 中国石油化工股份有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-108729269-A | A kind of active dye fixing agent and preparation method thereof | 李美琴 | 2018-11-02 | — | — | CN | claimed |
| CN-106046647-B | A kind of preparation method of the controllable compatilizer of polarity containing polyfunctional group | 河北工业大学 | 2018-07-31 | — | — | CN | claimed |
| CN-106046647-A | Method for preparing polyfunctional group containing compatilizer with controllable polarity | 河北工业大学 | 2016-10-26 | — | — | CN | claimed |
| CN-103788365-B | A kind of polyarylether and anion-exchange membrane and preparation method thereof containing quaternary ammonium lateral group | CHINA PETROLEUM & CHEMICAL CORP. (CN) | 2016-02-24 | — | — | CN | claimed |
| US-20250388705-A1 | WATER-SOLUBLE, BIODEGRADABLE DIHYDROXYALKYL CELLULOSE | ISP INVESTMENTS LLC (US) | 2025-12-25 | — | — | US | disclosed |
| US-4332935-A | Process for the production of cationic starch ethers | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388705-A1 | WATER-SOLUBLE, BIODEGRADABLE DIHYDROXYALKYL CELLULOSE | IDUA, ALG1, MGAM | CHRM2 2155/4885CHRM5 2152/4885CHRM3 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.