SCHEMBL455138

SCHEMBL455138

CCOC1C[CH]CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18169897 1.00
SCHEMBL18169999 1.00
SCHEMBL1040029 0.93 EPHX1 (0.33)
SCHEMBL5043492 0.91
SCHEMBL18169960 0.91
SCHEMBL18169700 0.91
SCHEMBL1039310 0.86 ALDH1A1 (0.32)
SCHEMBL1038975 0.86 ALDH1A1 (0.34)
SCHEMBL7981676 0.83 TAAR1 (0.36)
SCHEMBL1039174 0.80 NPC1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US claimed
CN-107531635-A Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-yl sulfonamides or salts thereof and their use for enhancing stress tolerance in plants 拜耳作物科学股份公司 2018-01-02 CN claimed
EP-3256448-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2017-12-20 EP claimed
WO-2016128365-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 WO claimed
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN disclosed
WO-2021106975-A1 HETEROCYCLIC COMPOUND 武田薬品工業株式会社 2021-06-03 WO disclosed
CN-111732499-A Process for producing cycloalkylalkyl ether compound 日本瑞翁株式会社 2020-10-02 CN disclosed
US-10766900-B2 Baricitinib intermediate, method for forming Baricitinib intermediate, and method for preparing Baricitinib or pharmaceutically acceptable salt thereof FORMOSA LABORATORIES, INC. (TW) 2020-09-08 US disclosed
US-20190202834-A1 BARICITINIB INTERMEDIATE, METHOD FOR FORMING BARICITINIB INTERMEDIATE, AND METHOD FOR PREPARING BARICITINIB OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FORMOSA LABORATORIES, INC. (TW) 2019-07-04 US disclosed
EP-2980056-B1 METHOD FOR PRODUCING CYCLOALKYL ALKYL ETHER COMPOUND ZEON CORP (JP) 2018-08-29 EP disclosed
US-20180199575-A1 SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-19 US disclosed
CN-1013493-B ESTERS OF DIHYDROLYSERGIC ACID LILLY CO ELI (US) 1991-08-14 CN disclosed
US-4968802-A ESTERIFICATION WITH ALKOXYCYCLOALKYL SULFONATE ELI LILLY AND COMPANY (US) 1990-11-06 US disclosed
US-4914100-A TREATING THROMBOSIS ELI LILLY AND COMPANY (US) 1990-04-03 US disclosed
US-4847261-A ANALGESICS, HYPOTENSIVES ELI LILLY AND COMPANY (US) 1989-07-11 US disclosed
US-4714704-A Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT receptor antagonists ELI LILLY AND COMPANY (US) 1987-12-22 US disclosed
EP-0219257-A2 Esters of dihydrolysergic acid ELI LILLY AND COMPANY (US) 1987-04-22 EP disclosed
CN-86106728-A ESTERS OF DIHYDROLYSERGIC ACID 1987-04-01 CN disclosed
US-3987054-A CORROSION INHIBITORS PLIVA PHARMACEUTICAL AND CHEMICAL WORKS (YU) 1976-10-19 US disclosed