Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28901039 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TSHRCA1CA2CA9 | |
| Acetic Acid SCHEMBL4152430 | 0.90 | FFAR3 (0.47) | ALDH1A1TSHRNFKB1THPOHSD17B10 | |
| SCHEMBL35686 | 0.84 | — | — | |
| Succinic Acid SCHEMBL15647083 | 0.82 | EGLN1 (0.50) | TSHRNFKB1PMP22FFAR3 | |
| Propionic Acid SCHEMBL4155424 | 0.82 | FFAR3 (0.56) | ALDH1A1TSHRFFAR3 | |
| SCHEMBL29475435 | 0.81 | — | — | |
| Bromide SCHEMBL29550005 | 0.81 | — | — | |
| Iodide SCHEMBL3681300 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL4147574 | 0.80 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| Trichloroacetic Acid SCHEMBL14958149 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695339-A1 | LATENT BASE CATALYST AND COATING COMPOSITION INCLUDING THE SAME | SWIMC LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024238605-A1 | LATENT BASE CATALYST AND COATING COMPOSITION INCLUDING THE SAME | SWIMC LLC (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-116444392-B | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-2613867-B1 | CO2 SCRUBBING PROCESS WITH AN ABSORBENT COMPRISING A NUCLEOPHILE AMINE AND NON-NUCLEOPHILIC BASE IN A NON-AQUEOUS SOLVENT | EXXONMOBIL RES & ENG CO (US) | 2018-05-02 | — | — | EP | disclosed |
| US-8715397-B2 | Mixed amine and non-nucleophilic base CO2 scrubbing process for improved adsorption at increased temperatures | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2613867-A1 | MIXED AMINE AND NON-NUCLEOPHILIC BASE CO2 SCRUBBING PROCESS FOR IMPROVED ADSORPTION AT INCREASED TEMPERATURES | ExxonMobil Research and Engineering Company (US) | 2013-07-17 | — | — | EP | disclosed |
| US-20120060686-A1 | Mixed Amine and Non-Nucleophilic Base CO2 Scrubbing Process for Improved Adsorption at Increased Temperatures | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2012034003-A1 | MIXED AMINE AND NON-NUCLEOPHILIC BASE CO2 SCRUBBING PROCESS FOR IMPROVED ADSORPTION AT INCREASED TEMPERATURES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| US-5969046-A | USING TERTIARY AMINES AND EPOXIDES AS MAIN ACTIVATOR OF MICHAEL CONDENSATION CURE PROCESS | ROHM AND HAAS COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0326723-B1 | METHOD FOR REACTING TWO COMPONENTS, COMPOSITIONS, COATING COMPOSITIONS AND USES THEREOF | ROHM AND HAAS COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0326723-A1 | Method for reacting two components, compositions, coating compositions and uses thereof | ROHM AND HAAS COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |