Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL14958149

CN(C)C(=N)N(C)C.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
TSHR P16473 3/20 0.53
TP53 P04637 1/20 0.53
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL2904243 0.80 TSHR (0.71) ALDH1A1TSHRTP53TDP1
Bicarbonate SCHEMBL455147 0.80 ALDH1A1 (0.39) ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL11789184 0.79 ALDH1A1 (0.30) ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL4147574 0.79 ALDH1A1 (0.30) ALDH1A1TSHR
Bicarbonate SCHEMBL28901039 0.77 ALDH1A1 (0.37) ALDH1A1TSHR
Acetic Acid SCHEMBL4152430 0.77 FFAR3 (0.47) ALDH1A1TSHR
Trichloroacetic Acid SCHEMBL8995195 0.73
SCHEMBL5579990 0.72
Trichloroacetic Acid SCHEMBL1331955 0.72
Trichloroacetic Acid SCHEMBL10493657 0.72 TSHR (1.00) ALDH1A1TSHRTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780385-B1 PROCESSES, PRODUCTS, AND COMPOSITIONS HAVING TETRAALKYLGUANIDINE SALT OF AROMATIC CARBOXYLIC ACID EVONIK OPERATIONS GMBH (DE) 2023-03-22 EP disclosed
EP-2725047-B1 Delay action catalyst for improving the stability of polyurethane systems having halogen containing blowing agents EVONIK OPERATIONS GMBH (DE) 2020-12-16 EP disclosed
US-10464876-B2 Processes, products, and compositions having tetraalkylguanidine salt of aromatic carboxylic acid EVONIK DEGUSSA GMBH (DE) 2019-11-05 US disclosed
US-10023681-B2 Delay action catalyst for improving the stability of polyurethane systems having halogen containing blowing agents EVONIK DEGUSSA GMBH (DE) 2018-07-17 US disclosed
US-20180065913-A1 Processes, products, and compositions having tetraalkylguanidine salt of aromatic carboxylic acid EVONIK OPERATIONS GMBH (DE) 2018-03-08 US disclosed
US-9765009-B2 Processes, products, and compositions having tetraalkylguanidine salt of aromatic carboxylic acid EVONIK DEGUSSA GMBH (DE) 2017-09-19 US disclosed
EP-2780385-A1 PROCESSES, PRODUCTS, AND COMPOSITIONS HAVING TETRAALKYLGUANIDINE SALT OF AROMATIC CARBOXYLIC ACID Air Products and Chemicals, Inc. (US) 2014-09-24 EP disclosed
EP-2725047-A1 Delay action catalyst for improving the stability of polyurethane systems having halogen containing blowing agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-04-30 EP disclosed
US-20140113984-A1 Delay Action Catalyst for Improving The Stability of Polyurethane Systems Having Halogen Containing Blowing Agents EVONIK OPERATIONS GMBH (DE) 2014-04-24 US disclosed
US-20130131276-A1 Processes, Products, and Compositions Having Tetraalkylguanidine Salt of Aromatic Carboxylic Acid AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-23 US disclosed
WO-2013074907-A1 PROCESSES, PRODUCTS, AND COMPOSITIONS HAVING TETRAALKYLGUANIDINE SALT OF AROMATIC CARBOXYLIC ACID AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-23 WO disclosed