⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743779 | 0.76 | — | — | |
| SCHEMBL7063130 | 0.72 | — | — | |
| SCHEMBL5555342 | 0.69 | — | — | |
| SCHEMBL2670280 | 0.69 | — | — | |
| SCHEMBL1402192 | 0.65 | — | — | |
| SCHEMBL324755 | 0.65 | — | — | |
| SCHEMBL8508228 | 0.62 | — | — | |
| SCHEMBL19553620 | 0.62 | — | — | |
| SCHEMBL27553160 | 0.55 | — | — | |
| SCHEMBL31558393 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367238-A1 | METHODS OF PLACING LOCKED NUCLEIC ACIDS IN SMALL INTERFERING RNA STRANDS | Switch Therapeutics Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-4367673-A1 | METHODS OF GENERATING CORE STRANDS IN CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES | Switch Therapeutics Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-4367672-A1 | METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA SENSORS | Switch Therapeutics Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023070057-A1 | CONDITION-ACTIVATABLE NUCLEIC ACID CONSTRUCTS AND THEIR USES FOR TREATING NEUROLOGICAL DISEASES | SWITCH THERAPEUTICS INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023283551-A1 | METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA SENSORS | SWITCH THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283553-A1 | METHODS OF GENERATING CORE STRANDS IN CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES | SWITCH THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283548-A1 | SIGNAL ACTIVATABLE NUCLEIC ACID CONSTRUCTS WITH WOBBLE BASE PAIRINGS | SWITCH THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283552-A1 | METHODS OF PLACING LOCKED NUCLEIC ACIDS IN SMALL INTERFERING RNA STRANDS | SWITCH THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| US-7585851-B2 | 3′-prodrugs of 2′-deoxy-β-L-nucleosides | IDENIX PHARMACEUTICALS, INC. (US) | 2009-09-08 | — | — | US | disclosed |