⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551663 | 0.72 | — | — | |
| SCHEMBL2634659 | 0.69 | — | — | |
| SCHEMBL1251785 | 0.66 | — | — | |
| SCHEMBL27553160 | 0.64 | — | — | |
| SCHEMBL324755 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL8470162 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL941846 | 0.60 | — | — | |
| SCHEMBL3305612 | 0.58 | — | — | |
| SCHEMBL17494529 | 0.58 | — | — | |
| SCHEMBL545834 | 0.54 | MPO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097939-B1 | Method for the synthesis of isoguanosine and of its 2'-derivatives | BAYER AG (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-0778898-B1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | BAYER AG (US) | 2002-11-13 | — | — | EP | disclosed |
| US-20010026918-A1 | Reduction of nonspecific hybridization by using novel base-pairing schemes | COLLINS MARK L (US) | 2001-10-04 | — | — | US | disclosed |
| US-6232462-B1 | SYNTHESIS OF AN ISOGUANOSINE DERIVATIVE USED AS ANTISENSE AND APTAMER THERAPEUTICS AND DRUG DISCOVERY | BAYER CORPORATION | 2001-05-15 | — | — | US | disclosed |
| EP-1097939-A2 | Method for the synthesis of isoguanosine and its 2'-derivatives | Bayer Corporation (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-1996006950-A9 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | — | 1997-05-09 | — | — | WO | disclosed |