SCHEMBL4551665

SCHEMBL4551665

C=CCc1nc2nc(N)ncc2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
RXFP1 Q9HBX9 1/20 0.35
CDK1 P06493 2/20 0.33
CCNB1 P14635 2/20 0.33
CCNA2 P20248 2/20 0.33
CDK2 P24941 2/20 0.33
CCNA1 P78396 2/20 0.33
MGMT P16455 1/20 0.33
DHFR P00374 2/20 0.33
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4241038 0.83 ALDH1A1 (0.41) ALDH1A1RXFP1
SCHEMBL5961402 0.81
SCHEMBL4388432 0.80 ALDH1A1 (0.39) ALDH1A1RXFP1
SCHEMBL28328648 0.78 ALDH1A1 (0.46) ALDH1A1RXFP1CDK1CCNB1CCNA2
SCHEMBL7175004 0.77 TP53 (0.32) ALDH1A1RXFP1CDK1CCNB1NPSR1
SCHEMBL31735186 0.77 GRM5 (0.31)
SCHEMBL4336356 0.77
SCHEMBL9363803 0.77 ALDH1A1 (0.36) ALDH1A1RXFP1
SCHEMBL8607902 0.76 MAPT (0.32)
SCHEMBL14743780 0.75 ALDH1A1 (0.43) ALDH1A1RXFP1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040191780-A1 Simple and efficient tissue culture process of producing viable plants of Decalepis hamiltonii using vescicular arbuscular mycorrhizae (VAM) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-30 US claimed
EP-4367673-A1 METHODS OF GENERATING CORE STRANDS IN CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES Switch Therapeutics Inc. (US) 2024-05-15 EP disclosed
EP-4367672-A1 METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA SENSORS Switch Therapeutics Inc. (US) 2024-05-15 EP disclosed
EP-4367238-A1 METHODS OF PLACING LOCKED NUCLEIC ACIDS IN SMALL INTERFERING RNA STRANDS Switch Therapeutics Inc. (US) 2024-05-15 EP disclosed
CN-116617233-A Methods of treating arenaviridae and coronaviridae viral infections 吉利德科学公司 2023-08-22 CN disclosed
WO-2023070057-A1 CONDITION-ACTIVATABLE NUCLEIC ACID CONSTRUCTS AND THEIR USES FOR TREATING NEUROLOGICAL DISEASES SWITCH THERAPEUTICS INC. (US) 2023-04-27 WO disclosed
CN-109776637-B Nucleoside phosphoramidate prodrugs 吉利德科学公司 2023-04-18 CN disclosed
CN-115887465-A Methods of treating arenaviridae and coronaviridae virus infections 吉利德科学公司 2023-04-04 CN disclosed
CN-115844896-A Methods of treating arenaviridae and coronaviridae virus infections 吉利德科学公司 2023-03-28 CN disclosed
WO-2023283553-A1 METHODS OF GENERATING CORE STRANDS IN CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES SWITCH THERAPEUTICS INC. (US) 2023-01-12 WO disclosed
CN-102989012-A Monitoring and modulating hgf/hgfr activity GEN HOSPITAL CORP 2013-03-27 CN disclosed
CN-101189023-B Monitoring and modulating hgf/hgfr activity GEN HOSPITAL CORP 2013-01-30 CN disclosed
CN-101681396-A Glucoprotein product that limits and associated method MOMENTA PHARMACEUTICALS INC 2010-03-24 CN disclosed
CN-101626777-A Immunophilin ligands and methods of modulating immunophilin and calcium channel activity WYETH CORP 2010-01-13 CN disclosed
US-7585851-B2 3′-prodrugs of 2′-deoxy-β-L-nucleosides IDENIX PHARMACEUTICALS, INC. (US) 2009-09-08 US disclosed
CN-101405408-A Method for enhancing lymphatic function GEN HOSPITAL CORP (US) 2009-04-08 CN disclosed
CN-101189023-A Monitoring and modulating HGF/HGFR activity GEN HOSPITAL CORP (US) 2008-05-28 CN disclosed
US-20040191780-A1 Simple and efficient tissue culture process of producing viable plants of Decalepis hamiltonii using vescicular arbuscular mycorrhizae (VAM) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-30 US disclosed
CN-1326510-A Method for obtaining genetically modified plants, plant material and plant habitat obtainable by this method GENESIS RES & DEV CORP LTD (NZ) 2001-12-12 CN disclosed
US-6242257-B1 CUTTING APICAL EXPLANT FROM GERMINATED COTTON SEEDLING, CULTURING FOR SHOOT PROLIFERATION IN MEDIUM FREE OF AUXIN AND SUCROSE, HARVESTING SHOOTS, THEN CULTURING EACH SHOOT IN SECOND MEDIUM; EFFICIENT PROCESS FOR GENETIC ENGINEERING COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2001-06-05 US disclosed