Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175004 | 0.87 | TP53 (0.32) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL9706008 | 0.78 | NOS3 (0.40) | MAPK1 | |
| SCHEMBL5961402 | 0.76 | — | — | |
| SCHEMBL4551665 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL31735186 | 0.75 | GRM5 (0.31) | MAPTTP53 | |
| SCHEMBL4336356 | 0.72 | — | — | |
| SCHEMBL1079071 | 0.71 | METAP2 (0.41) | — | |
| SCHEMBL1436458 | 0.71 | KDM4C (0.34) | — | |
| SCHEMBL9515916 | 0.70 | — | — | |
| SCHEMBL1235371 | 0.69 | MAT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011121-A1 | BIOLOGICALLY ACTIVE PHOSPHOTRIESTER-TYPE COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1998-03-19 | — | — | WO | disclosed |