Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884035 | 0.88 | HDAC1 (0.70) | HDAC1HDAC6 | |
| SCHEMBL17842764 | 0.82 | TBXAS1 (0.52) | BCL2L1HDAC1TBXAS1GPR35HDAC6 | |
| SCHEMBL17347192 | 0.82 | NR4A2 (0.54) | BCL2L1NR4A2 | |
| SCHEMBL3570753 | 0.81 | HDAC1 (0.57) | BCL2L1HDAC1TBXAS1 | |
| SCHEMBL26110644 | 0.79 | TBXAS1 (0.50) | BCL2L1HDAC1TBXAS1GPR35 | |
| SCHEMBL31207829 | 0.79 | TBXAS1 (0.57) | BCL2L1HDAC1TBXAS1GPR35HDAC6 | |
| SCHEMBL191611 | 0.79 | TBXAS1 (0.57) | BCL2L1HDAC1TBXAS1GPR35HDAC6 | |
| SCHEMBL153980 | 0.77 | MEN1 (0.57) | BCL2L1HDAC1TBXAS1GPR35HDAC6 | |
| SCHEMBL26107968 | 0.77 | TBXAS1 (0.56) | BCL2L1HDAC1TBXAS1GPR35HDAC6 | |
| SCHEMBL4255241 | 0.76 | HDAC1 (0.82) | BCL2L1HDAC1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677731-A4 | THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES | ATON PHARMA INC (US) | 2009-05-06 | — | — | EP | claimed |
| EP-1677731-A2 | THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES | Aton Pharma, Inc. (US) | 2006-07-12 | — | — | EP | claimed |
| WO-2005034880-A2 | THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES | ATON PHARMA, INC. (US) | 2005-04-21 | — | — | WO | claimed |