Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185505 | 0.92 | CCR5 (0.68) | CCR5KCNH2 | |
| SCHEMBL14185474 | 0.91 | CCR5 (0.64) | CCR5KCNH2 | |
| SCHEMBL14185417 | 0.89 | CCR5 (0.59) | CCR5KCNH2 | |
| SCHEMBL4552548 | 0.86 | CCR5 (0.60) | CCR5KCNH2 | |
| SCHEMBL14185374 | 0.83 | CCR5 (0.53) | CCR5KCNH2 | |
| SCHEMBL14185345 | 0.83 | CCR5 (0.55) | CCR5KCNH2 | |
| SCHEMBL14185344 | 0.82 | CCR5 (0.49) | CCR5KCNH2 | |
| SCHEMBL14184985 | 0.80 | CCR5 (0.55) | CCR5KCNH2 | |
| SCHEMBL14184996 | 0.80 | CCR5 (0.54) | CCR5KCNH2 | |
| SCHEMBL4551933 | 0.78 | CCR5 (0.73) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |