Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498015 | 0.82 | SLC18A3 (0.42) | AVPR1A | |
| SCHEMBL3759047 | 0.82 | SLC18A3 (0.42) | AVPR1A | |
| SCHEMBL3759045 | 0.82 | SLC18A3 (0.42) | AVPR1A | |
| SCHEMBL4551935 | 0.80 | CCR5 (0.56) | CCR5 | |
| SCHEMBL4552558 | 0.78 | CCR5 (0.47) | CCR5 | |
| SCHEMBL14184972 | 0.77 | CCR5 (0.70) | CCR5 | |
| SCHEMBL4551923 | 0.77 | CCR5 (0.65) | CCR5 | |
| SCHEMBL4209312 | 0.75 | CCR5 (0.56) | CCR5 | |
| SCHEMBL13969447 | 0.74 | CCR5 (0.68) | CCR5 | |
| SCHEMBL14184973 | 0.73 | CCR5 (0.72) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |