Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551935 | 0.87 | CCR5 (0.56) | CCR5 | |
| SCHEMBL4597902 | 0.84 | CCR5 (0.44) | CCR5 | |
| SCHEMBL5573859 | 0.84 | CCR5 (0.44) | CCR5 | |
| SCHEMBL4551923 | 0.83 | CCR5 (0.65) | CCR5 | |
| SCHEMBL4209312 | 0.82 | CCR5 (0.56) | CCR5 | |
| SCHEMBL14185329 | 0.80 | CCR5 (0.75) | CCR5 | |
| SCHEMBL4012998 | 0.79 | CCR5 (0.69) | CCR5 | |
| SCHEMBL13969447 | 0.79 | CCR5 (0.68) | CCR5 | |
| SCHEMBL4552097 | 0.78 | CCR5 (0.41) | CCR5 | |
| SCHEMBL4013527 | 0.77 | CCR5 (0.69) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |