SCHEMBL4552187

SCHEMBL4552187

Cc1cc(C2(c3ccc(OC=O)c(C)c3)c3ccccc3-c3ccccc32)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.70
ESR2 Q92731 3/20 0.70
KMT2A Q03164 6/20 0.48
MEN1 O00255 5/20 0.48
LMNA P02545 4/20 0.48
MAPT P10636 4/20 0.48
POLB P06746 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
XBP1 P17861 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 1/20 0.35
OPRK1 P41145 1/20 0.35
CHRM5 P08912 4/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX12 P18054 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13709462 0.87 ESR1 (0.50) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL1847909 0.84 ESR1 (0.78) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL29462974 0.84 ESR1 (0.78) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL22416797 0.84 ESR1 (0.47) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL70957 0.84 ESR1 (1.00) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL29450641 0.84 ESR1 (1.00) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL29358768 0.84 ESR1 (1.00) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL11957102 0.84 ESR1 (0.56) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL22651232 0.82 ESR1 (0.70) ESR1ESR2KMT2AMEN1LMNA
SCHEMBL15691554 0.82 ESR1 (0.97) ESR1ESR2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3138876-A1 POLYCARBONATE RESIN COMPOSITION, AND OPTICAL MATERIAL AND OPTICAL LENS EACH MANUFACTURED USING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2017-03-08 EP disclosed
US-20170051146-A1 POLYCARBONATE RESIN COMPOSITION, AND OPTICAL MATERIAL AND OPTICAL LENS EACH MANUFACTURED USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-02-23 US disclosed
US-9360593-B2 Polycarbonate resin, production method therefor, and optical molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-07 US disclosed
US-20150285954-A1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-10-08 US disclosed
EP-2918621-A1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY Mitsubishi Gas Chemical Company, Inc. (JP) 2015-09-16 EP disclosed
WO-2014073496-A1 POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY 三菱瓦斯化学株式会社 (JP) 2014-05-15 WO disclosed
US-8710157-B2 Contact lens material MENICON CO., LTD. (JP) 2014-04-29 US disclosed
US-20120116028-A1 METHOD FOR PRODUCING POLYCARBONATE MATERIAL HAVING EXCELLENT SOLUBILITY AND AFFINITY, AND CONTACT LENS MATERIAL COMPRISING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-10 US disclosed
US-20120116019-A1 CONTACT LENS MATERIAL MENICON CO., LTD. (JP) 2012-05-10 US disclosed
US-8173720-B2 Transparent gel and contact lense from the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-08 US disclosed
US-7803507-B2 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2010-09-28 US disclosed
US-7700714-B2 Optical element and achromatic lens TEIJIN CHEMICALS, LTD. (JP) 2010-04-20 US disclosed
US-20090143560-A1 Optical Element and Achromatic Lens TEIJIN CHEMICALS, LTD. 2009-06-04 US disclosed
US-7527906-B2 Imaging member having adjustable friction anticurl back coating XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20090012205-A1 TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-01-08 US disclosed
US-20070292797-A1 Imaging member having adjustable friction anticurl back coating XEROX CORPORATION (US) 2007-12-20 US disclosed
EP-1840167-A1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO., LTD. (JP) 2007-10-03 EP disclosed
US-20070026334-A1 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2007-02-01 US disclosed