SCHEMBL4552590

SCHEMBL4552590

C=CCC(CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 8/20 0.56
GRIK1 P39086 2/20 0.52
GRIK2 Q13002 2/20 0.52
GSR P00390 1/20 0.48
RNPEP Q9H4A4 1/20 0.47
CPA1 P15085 1/20 0.46
TBXAS1 P24557 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PLG P00747 1/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
SLC6A2 P23975 1/20 0.39
RECQL P46063 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785041 0.98 CPB2 (0.59) CPB2GRIK1GRIK2GSRRNPEP
SCHEMBL6834831 0.94 CPB2 (0.57) CPB2GRIK1GRIK2GSRRNPEP
SCHEMBL13258636 0.86 GRIK1 (0.57) CPB2GRIK1GRIK2GSRRNPEP
SCHEMBL14518785 0.86 GRIK1 (0.57) CPB2GRIK1GRIK2GSRRNPEP
SCHEMBL11795592 0.82 ABCC4 (0.50) GRIK1GRIK2CPA1CYP2D6NFKB1
SCHEMBL11796940 0.81 ABCC4 (0.53) GRIK1GRIK2CPA1CYP2D6NFKB1
SCHEMBL11784979 0.81 ABCC4 (0.53) GRIK1GRIK2CPA1CYP2D6NFKB1
SCHEMBL11753937 0.81 MAPT (0.53) CPB2GRIK1GRIK2CPA1TBXAS1
SCHEMBL16041974 0.81 MAPT (0.53) CPB2GRIK1GRIK2CPA1TBXAS1
SCHEMBL9733024 0.81 GRIK1 (0.52) CPB2GRIK1GRIK2CPA1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062203-B2 PROCESS FOR THE CONTINUOUS PURIFICATION OF CRUDE EPSILON-CAPROLACTAM DSM IP ASSETS BV (NL) 2009-10-21 EP claimed
EP-1335904-B1 PRODUCTION OF ALKYL 6-AMINOCAPROATE INVISTA TECH SARL (US) 2006-03-08 EP claimed
EP-1062203-B1 PROCESS FOR THE CONTINUOUS PURIFICATION OF CRUDE EPSILON-CAPROLACTAM DSM NV (NL) 2002-07-03 EP claimed