Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552590 | 0.94 | CPB2 (0.56) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL10785041 | 0.92 | CPB2 (0.59) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL13258636 | 0.88 | GRIK1 (0.57) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL14518785 | 0.88 | GRIK1 (0.57) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL9733024 | 0.82 | GRIK1 (0.52) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL2135519 | 0.82 | GRIK1 (0.50) | CPB2GRIK1GRIK2CPA1TBXAS1 | |
| SCHEMBL1370161 | 0.80 | CPB2 (0.74) | CPB2GSRRNPEPCA2MAPK1 | |
| SCHEMBL11795592 | 0.80 | ABCC4 (0.50) | GRIK1GRIK2CPA1CYP2D6NFKB1 | |
| SCHEMBL7752392 | 0.80 | FOLH1 (0.52) | GRIK1GRIK2CPA1CYP2D6NFKB1 | |
| SCHEMBL2081268 | 0.80 | CA2 (0.61) | GRIK1GRIK2CPA1TBXAS1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753449-B2 | ALLYL-5-AMINOPENTANOIC ACID/2-/ COVALENTLY ATTACHED TO AN AGAROSE OR POLYSTYRENE SOLID SUPPORTS; USE FOR BUILDING PHARMACEUTICAL DRUGS COLLECTIONS LIBRARIES | ARQULE, INC. | 2004-06-22 | — | — | US | disclosed |
| US-20030096301-A1 | Linker for solid-phase synthesis | ARQULE, INC. | 2003-05-22 | — | — | US | disclosed |