Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.41 |
| ▸ | DRD1 | P21728 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360447 | 1.00 | DRD2 (0.41) | DRD2DRD1OPRK1ESR2NR1H2 | |
| SCHEMBL4552915 | 1.00 | DRD2 (0.41) | DRD2DRD1OPRK1ESR2NR1H2 | |
| SCHEMBL1362677 | 0.87 | DRD2 (0.46) | DRD2DRD1ESR2NR1H2 | |
| SCHEMBL1559613 | 0.87 | DRD2 (0.46) | DRD2DRD1ESR2NR1H2 | |
| SCHEMBL1559611 | 0.87 | DRD2 (0.46) | DRD2DRD1ESR2NR1H2 | |
| SCHEMBL1560073 | 0.86 | DRD2 (0.42) | DRD2DRD1ALDH1A1POLBADRB2 | |
| SCHEMBL1560069 | 0.86 | DRD2 (0.42) | DRD2DRD1ALDH1A1POLBADRB2 | |
| SCHEMBL4551311 | 0.81 | DRD2 (0.62) | DRD2DRD1 | |
| SCHEMBL4551313 | 0.81 | DRD2 (0.62) | DRD2DRD1 | |
| SCHEMBL1360527 | 0.81 | DRD2 (0.62) | DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | COMT, PNMT, TYR | DRD2 210/4885DRD1 515/4885OPRK1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.