Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 3/20 | 0.31 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2817452 | 0.81 | F10 (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL7422047 | 0.79 | HDAC3 (0.34) | ATMRECQLKMT2ANLRP3KDM4E | |
| Trifluoroacetic Acid SCHEMBL7423282 | 0.78 | HRH2 (0.35) | KMT2AHRH2GPR6 | |
| Trifluoroacetic Acid SCHEMBL2329902 | 0.78 | F10 (0.35) | KMT2AHDAC8HRH2GPR6 | |
| Trifluoroacetic Acid SCHEMBL7421271 | 0.78 | F10 (0.35) | KMT2AHDAC8HRH2GPR6 | |
| Trifluoroacetic Acid SCHEMBL7419576 | 0.78 | DPP4 (0.39) | KMT2AHDAC3HDAC2HDAC8NCOR2 | |
| Trifluoroacetic Acid SCHEMBL8834439 | 0.78 | F10 (0.35) | KMT2AHDAC8HRH2GPR6 | |
| Trifluoroacetic Acid SCHEMBL7423939 | 0.76 | OPRD1 (0.36) | KMT2AHRH2 | |
| Trifluoroacetic Acid SCHEMBL7423834 | 0.76 | ALDH1A1 (0.37) | ATMKMT2ANLRP3ALDH1A1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7421816 | 0.75 | NPY1R (0.38) | KMT2AHRH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2006102674-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | NPC1L1, CYP46A1, NPC1 | ATM 4804/4885PARP1 4714/4885PLA2G1B 2532/4885 |
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | ATM 4204/4885PARP1 524/4885PLA2G1B 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.