Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MC5R | P33032 | 2/20 | 0.54 |
| ▸ | MC3R | P41968 | 2/20 | 0.54 |
| ▸ | MC1R | Q01726 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289901 | 0.82 | HDAC1 (0.76) | HTR6KMT2AMC5RMC3RMC1R | |
| Hydroxyamine SCHEMBL4563302 | 0.81 | HDAC1 (0.61) | HTR6KMT2AMC5RMC3RMC1R | |
| SCHEMBL23745517 | 0.79 | MC5R (0.71) | HTR6KMT2AMC5RMC3RMC1R | |
| SCHEMBL4563301 | 0.79 | HDAC1 (0.60) | HTR6KMT2AMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL23722207 | 0.78 | MC5R (0.69) | HTR6KMT2AMC5RMC3RMC1R | |
| SCHEMBL830201 | 0.77 | MC5R (0.79) | HTR6KMT2AMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL11188453 | 0.75 | MC5R (0.77) | HTR6KMT2AMC5RMC3RMC1R | |
| SCHEMBL18088393 | 0.75 | MC5R (0.71) | KMT2AMC5RMC3RMC1RHDAC1 | |
| SCHEMBL6037918 | 0.75 | MC5R (0.71) | HTR6KMT2AMC5RMC3RMC1R | |
| SCHEMBL17117861 | 0.75 | MC5R (0.71) | HTR6KMT2AMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682538-A4 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2009-05-27 | — | — | EP | disclosed |
| EP-1682538-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*Bio Pte Ltd (SG) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005040161-A1 | BIARYL LINKED HYDROXAMATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |