SCHEMBL830201

SCHEMBL830201

c1ccc(CNCCc2c[nH]c3ccccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MC5R P33032 2/20 0.79
MC3R P41968 2/20 0.79
MC1R Q01726 2/20 0.79
KMT2A Q03164 3/20 0.72
HTR2A P28223 4/20 0.68
G6PD P11413 1/20 0.64
HTR6 P50406 3/20 0.64
HTR1A P08908 2/20 0.64
DRD2 P14416 1/20 0.64
HTR7 P34969 1/20 0.64
MEN1 O00255 1/20 0.63
LMNA P02545 1/20 0.63
TP53 P04637 1/20 0.63
HDAC3 O15379 1/20 0.62
HDAC4 P56524 1/20 0.62
KCNH2 Q12809 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC7 Q8WUI4 1/20 0.62
HDAC2 Q92769 1/20 0.62
HDAC10 Q969S8 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11188453 0.98 MC5R (0.77) MC5RMC3RMC1RKMT2AHTR2A
Cyanide SCHEMBL30873705 0.96 MC5R (0.73) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL23745517 0.91 MC5R (0.71) MC5RMC3RMC1RKMT2AHTR2A
Hydrochloric Acid SCHEMBL23722207 0.90 MC5R (0.69) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL6635277 0.90 SLC6A4 (0.67) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL6165432 0.89 MC5R (0.71) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL798249 0.89 MC1R (1.00) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL18088393 0.88 MC5R (0.71) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL6037918 0.88 MC5R (0.71) MC5RMC3RMC1RKMT2AHTR2A
SCHEMBL17117861 0.88 MC5R (0.71) MC5RMC3RMC1RKMT2AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164504-A Indole compound and preparation method and application thereof 贵州省天然产物研究中心 2023-12-05 CN claimed
CN-114853820-A Ferrocene and camphorsulfonic acid composite derivative, preparation method thereof and application thereof in catalyzing asymmetric P-S reaction 江苏医药职业学院 2022-08-05 CN claimed
CN-104530047-A Canthium dicoccum-6-one quaternary ammonium salt and preparation method and applicaton thereof UNIV NORTHWEST A&F 2015-04-22 CN claimed
US-20260138947-A1 BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2026-05-21 US disclosed
US-20260138947-A1 BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2026-05-21 US disclosed
US-20260042735-A1 BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2026-02-12 US disclosed
US-20260042735-A1 BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2026-02-12 US disclosed
EP-4423061-A4 NOVEL BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2025-09-10 EP disclosed
US-20240400510-A1 NOVEL BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2024-12-05 US disclosed
US-20240400510-A1 NOVEL BENZYLTRYPTAMINE COMPOUNDS REUNION NEUROSCIENCE INC (US) 2024-12-05 US disclosed
EP-4423061-A1 NOVEL BENZYLTRYPTAMINE COMPOUNDS Reunion Neuroscience, Inc. (US) 2024-09-04 EP disclosed
WO-2008046232-A1 AZIRIDINE ALDEHYDES, AZIRIDINE-CONJUGATED AMINO DERIVATIVES, AZIRIDINE-CONJUGATED BIOMOLECULES AND PROCESSES FOR THEIR PREPARATION YUDIN ANDREI K (CA) 2008-04-24 WO disclosed
US-4843080-A VASODILATION; CARDIOVASCULAR ACTIVITY; CHEMICAL INTERMEDIATES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1989-06-27 US disclosed
EP-0187122-A2 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes CIBA-GEIGY AG (CH) 1986-07-09 EP disclosed
US-4524073-A β-Lactam compounds BEECHAM GROUP P.1.C. (GB) 1985-06-18 US disclosed
EP-0101199-A1 Beta-lactam compounds BEECHAM GROUP PLC (GB) 1984-02-22 EP disclosed
US-4425351-A ANTIANOXIC SYNTHELABO (FR) 1984-01-10 US disclosed
EP-0089926-A2 Pharmaceutical preparations of tetracycles containing nitrogen, and compounds of this type CIBA-GEIGY AG (CH) 1983-09-28 EP disclosed
US-4367230-A ANTIANOXIC AGENTS TANABE SEIYAKU CO., LTD. (JP) 1983-01-04 US disclosed
US-4228168-A ANTI-ANOXIC ACTIVITY TANABE SEIYAKU CO., LTD. (JP) 1980-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400510-A1 NOVEL BENZYLTRYPTAMINE COMPOUNDS HTR2C, HTR2A, HTR3B MC5R 152/4885MC3R 169/4885MC1R 505/4885
US-20260042735-A1 BENZYLTRYPTAMINE COMPOUNDS HTR2C, HTR2A, HTR6 MC5R 52/4885MC3R 137/4885MC1R 579/4885
US-20260138947-A1 BENZYLTRYPTAMINE COMPOUNDS HTR2C, CNR2, HTR3B MC5R 80/4885MC3R 149/4885MC1R 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.