Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552040 | 0.85 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4DHFRDPP7 | |
| SCHEMBL4552893 | 0.83 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4DPP7 | |
| SCHEMBL11882612 | 0.80 | MMP1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL15635204 | 0.80 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL8395460 | 0.80 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFRDPP7 | |
| SCHEMBL4553207 | 0.80 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8394606 | 0.77 | SLC6A2 (0.43) | SLC6A3SLC6A2SLC6A4ALDH1A1LMNA | |
| SCHEMBL6050465 | 0.77 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL24654963 | 0.76 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4DPP7 | |
| SCHEMBL26488994 | 0.76 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612207-B1 | Processes and intermediates for preparing 2-substituted piperidine stereoisomers | CELGENE CORP (US) | 2009-01-07 | — | — | EP | claimed |
| EP-1612207-A1 | Processes and intermediates for preparing 2-substituted piperidine stereoisomers | CELGENE CORPORATION (US) | 2006-01-04 | — | — | EP | claimed |
| EP-1612207-B1 | Processes and intermediates for preparing 2-substituted piperidine stereoisomers | CELGENE CORP (US) | 2009-01-07 | — | — | EP | disclosed |