Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518994 | 0.84 | CDC25B (0.70) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL29752528 | 0.82 | LMNA (0.46) | CDC25BMAOAIDO1MAOBAKT1 | |
| Methane SCHEMBL28470631 | 0.82 | CDC25B (0.67) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL170468 | 0.72 | LMNA (0.43) | CDC25BMAOAIDO1MAOBAKT1 | |
| SCHEMBL29481018 | 0.69 | S100A4 (0.58) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL5712107 | 0.69 | S100A4 (0.58) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL18745224 | 0.68 | MEN1 (0.61) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL3141116 | 0.67 | S100A4 (0.63) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL933891 | 0.67 | S100A4 (0.63) | SLC2A1CDC25BMAOAIDO1MAOB | |
| SCHEMBL4368339 | 0.66 | MEN1 (0.61) | CDC25BMAOAIDO1MAOBAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3251582-B2 | — | — | 2002-01-28 | — | — | JP | claimed |
| US-5763479-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS | KS BIOMEDIX LTD. (GB) | 1998-06-09 | — | — | US | claimed |
| EP-0570414-A1 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | KS BIOMEDIX LTD. (GB) | 1993-11-24 | — | — | EP | claimed |
| WO-1992013532-A2 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | CHAYEN JOSEPH (GB) | 1992-08-20 | — | — | WO | claimed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | claimed |
| WO-2008016085-A9 | ISOINDOLES, COMPOUNDS PREPARED FROM THE SAME, AND PROCESSES FOR PRODUCTION OF BOTH | NIPPON CATALYTIC CHEM IND (JP) | 2009-07-16 | — | — | WO | disclosed |
| EP-0570414-B1 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | KS BIOMEDIX LTD (GB) | 2000-07-05 | — | — | EP | disclosed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0394563-B1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA GEVAERT NV (BE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0570414-A1 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | KS BIOMEDIX LTD. (GB) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992013532-A3 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | CHAYEN JOSEPH (GB) | 1992-10-29 | — | — | WO | disclosed |
| EP-0376776-B1 | PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE | L'OREAL (FR) | 1992-09-23 | — | — | EP | disclosed |
| WO-1992013532-A2 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | CHAYEN JOSEPH (GB) | 1992-08-20 | — | — | WO | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |
| US-5021393-A | Stable quinonediimine dyes | AGFA-GEVAERT, N.V. (BE) | 1991-06-04 | — | — | US | disclosed |
| EP-0394563-A1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA-GEVAERT N.V. (BE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | disclosed |
| US-4064139-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, ANTI-PARKINSON'S DISEASE | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |