⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005701 | 0.83 | CNR2 (0.39) | — | |
| SCHEMBL4432930 | 0.79 | SKP2 (0.42) | — | |
| SCHEMBL10367130 | 0.79 | — | — | |
| SCHEMBL6300221 | 0.78 | PTGS2 (0.41) | — | |
| SCHEMBL2128069 | 0.77 | — | — | |
| SCHEMBL1631246 | 0.77 | — | — | |
| SCHEMBL14935565 | 0.77 | — | — | |
| SCHEMBL2497498 | 0.77 | HRH3 (0.45) | — | |
| SCHEMBL6299128 | 0.77 | GABRA1 (0.40) | — | |
| SCHEMBL2500621 | 0.77 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169003-A | Catalyst systems for preparing 1-hexene and/or 1-octene from ethylene | SK INNOVATION CO LTD | 2014-11-26 | — | — | CN | claimed |
| US-8071625-B2 | E.g., [(1-(2-aminoacetyl)-4-{N-[(3-fluoro-2-methylphenyl)methyl]carbamoyl}(4-piperidyl))methoxy]-N-(4-ethylphenyl)carboxamide; smooth muscle myosin or non-muscle myosin modulator; hypotensive agent; asthma, COPD, bronchoconstrictive disease, glaucoma, pre-menstrual cramps, erectile dysfunction | CYTOKINETICS, INC. (US) | 2011-12-06 | — | — | US | claimed |
| US-20080234259-A1 | Novel Cannabinoid Receptor Ligands, Pharmaceutical Compositions Containing Them, and Process For Their Preparation | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-09-25 | — | — | US | claimed |
| WO-2008016676-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | claimed |
| EP-0805677-B1 | EXTENDED RELEASE CLONIDINE FORMULATION | HORACEK H JOSEPH (US) | 2005-06-15 | — | — | EP | claimed |
| EP-0256798-B1 | ANAESTHETIC COMPOSITION | Anaquest, Inc. (US) | 1991-09-25 | — | — | EP | claimed |
| US-4859685-A | Anesthetic composition and method of using the same | BOC, INC. (US) | 1989-08-22 | — | — | US | claimed |
| EP-0256798-A1 | Anaesthetic composition | Anaquest, Inc. (US) | 1988-02-24 | — | — | EP | claimed |
| US-4629495-A | Herbicidal 5-amino-4-cyano-1-phenylpyrazoles | MAY & BAKER LIMITED (GB) | 1986-12-16 | — | — | US | claimed |
| WO-2020061412-A1 | COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016145614-A1 | TRIAZOLYL PYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-22 | — | — | WO | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| EP-0327808-A1 | Substituted 3-aminosydnonimines, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0256798-A1 | Anaesthetic composition | Anaquest, Inc. (US) | 1988-02-24 | — | — | EP | disclosed |
| US-4629495-A | Herbicidal 5-amino-4-cyano-1-phenylpyrazoles | MAY & BAKER LIMITED (GB) | 1986-12-16 | — | — | US | disclosed |
| EP-0031295-B1 | ORGANIC ANTIMONY-SULPHUR COMPOUNDS, THEIR USE AS STABILISERS IN CHLORIC THERMOPLASTICS, AND THERMOPLASTICS SO STABILISED | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| US-4367304-A | Novel organic antimony-sulfur compounds and their use as stabilizers for chlorine-containing thermoplasts | CIBA-GEIGY CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |