SCHEMBL4553382

SCHEMBL4553382

Cc1cccc(-c2ccc(-c3ccc(-c4cccc(C)c4)c(-c4cccc(C)c4)c3N)c(N)c2-c2cccc(C)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
HEXA P06865 1/20 0.47
HEXB P07686 1/20 0.47
ADORA1 P30542 2/20 0.44
MAP4K4 O95819 2/20 0.44
CHEK1 O14757 1/20 0.44
ABL1 P00519 1/20 0.44
NTRK1 P04629 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
CSF1R P07333 1/20 0.44
MET P08581 1/20 0.44
PDGFRB P09619 1/20 0.44
PIM1 P11309 1/20 0.44
FGFR1 P11362 1/20 0.44
PDGFRA P16234 1/20 0.44
PRKACA P17612 1/20 0.44
LTK P29376 1/20 0.44
GRK5 P34947 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566795 0.93 RAB9A (0.47) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL10441622 0.85 RAB9A (0.43) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL11629135 0.81 RAB9A (0.50) RAB9AHEXAHEXBADORA1MAP4K4
Ammonia Solution, Strong SCHEMBL29089079 0.79 RAB9A (0.49) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL28942707 0.78 RAB9A (0.47) RAB9AADORA1MAP4K4CHEK1ABL1
SCHEMBL6662358 0.78 RAB9A (0.50) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL7164278 0.77 ALDH1A1 (0.42) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL6422117 0.77 RAB9A (0.41) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL4058897 0.77 RAB9A (0.46) RAB9AHEXAHEXBADORA1MAP4K4
SCHEMBL29416513 0.77 RAB9A (0.46) RAB9AADORA1MAP4K4CHEK1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622231-B2 Imaging members containing intermixed polymer charge transport component layer XEROX CORPORATION (US) 2009-11-24 US disclosed
US-20080057426-A1 Photoconductors XEROX CORPORATION 2008-03-06 US disclosed