Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553472 | 1.00 | FOLH1 (0.56) | FOLH1LTA4HMMECTSKANPEP | |
| SCHEMBL10878767 | 0.83 | MME (0.62) | LTA4HMME | |
| SCHEMBL8862574 | 0.82 | MME (0.52) | LTA4HMMECTSK | |
| SCHEMBL8862571 | 0.82 | MME (0.52) | LTA4HMMECTSK | |
| SCHEMBL5557381 | 0.81 | LTA4H (0.47) | LTA4HMMECTSK | |
| SCHEMBL5099185 | 0.81 | MME (0.54) | FOLH1LTA4HMMECTSK | |
| SCHEMBL5099195 | 0.81 | MME (0.54) | FOLH1LTA4HMMECTSK | |
| SCHEMBL222158 | 0.80 | CTSK (0.76) | MMECTSK | |
| SCHEMBL1823902 | 0.80 | CTSK (0.76) | MMECTSK | |
| SCHEMBL2366985 | 0.80 | CTSK (0.76) | MMECTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754475-B1 | Use of C-terminal modified oxamyl dipeptides as inhibitors of the ice/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS INC (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-1754475-A1 | Use of C-terminal modified oxamyl dipeptides as inhibitors of the ice/ced-3 family of cysteine proteases | Idun Pharmaceuticals, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |