Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673186 | 0.98 | KDM4E (0.52) | KDM4EGPR3HTR6TOP2APARP1 | |
| Iodide SCHEMBL4717590 | 0.98 | KDM4E (0.52) | KDM4EGPR3HTR6TOP2APARP1 | |
| Hydrochloric Acid SCHEMBL3881151 | 0.98 | KDM4E (0.52) | KDM4EGPR3HTR6TOP2APARP1 | |
| Hydrochloric Acid SCHEMBL28761791 | 0.96 | KDM4E (0.50) | KDM4EGPR3HTR6TOP2APARP1 | |
| Hydrochloric Acid SCHEMBL27669383 | 0.96 | KDM4E (0.50) | KDM4EGPR3HTR6TOP2APARP1 | |
| Toluene SCHEMBL19252764 | 0.90 | KDM4E (0.44) | KDM4EGPR3HTR6TOP2APARP1 | |
| Chlorobenzene SCHEMBL19252790 | 0.90 | HDAC6 (0.46) | KDM4EGPR3HTR6TOP2ASMN1; SMN2 | |
| Formic Acid SCHEMBL3882912 | 0.90 | KDM4E (0.44) | KDM4EGPR3HTR6TOP2APARP1 | |
| Acetic Acid SCHEMBL18155003 | 0.89 | KDM4E (0.43) | KDM4EGPR3HTR6ALOX15RAD52 | |
| SCHEMBL574757 | 0.87 | KDM4E (0.42) | KDM4EGPR3HTR6RAD52SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4195924-A1 | DISINFECTANT COMPOSITION | Helperby Therapeutics Limited (GB) | 2023-06-21 | — | — | EP | claimed |
| WO-2022038351-A1 | DISINFECTANT COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | WO | claimed |
| WO-2019180176-A1 | COMPOSITION FOR THE TREATMENT OF SCHIZOPHRENIA AND/OR PSYCHOSIS | SPHERIUM BIOMED, S.L. (ES) | 2019-09-26 | — | — | WO | claimed |
| EP-3368031-A1 | TRIPLE COMBINATION | Helperby Therapeutics Limited (GB) | 2018-09-05 | — | — | EP | claimed |
| CN-108289878-A | Triple combination | 赫尔普百治疗有限公司 | 2018-07-17 | — | — | CN | claimed |
| EP-3283178-A1 | ORAL COMPOSITION | Helperby Therapeutics Limited (GB) | 2018-02-21 | — | — | EP | claimed |
| CN-107602570-A | A kind of nitrogenous polynary and heterocyclic compound method of synthesis | 暨南大学 | 2018-01-19 | — | — | CN | claimed |
| WO-2017072488-A1 | TRIPLE COMBINATION | HELPERBY THERAPEUTICS LIMITED (GB) | 2017-05-04 | — | — | WO | claimed |
| WO-2016166515-A1 | ORAL COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2016-10-20 | — | — | WO | claimed |
| EP-2624817-A1 | NOVEL COMPOSITION | Helperby Therapeutics Limited (GB) | 2013-08-14 | — | — | EP | claimed |
| EP-1945211-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | Helperby Therapeutics Limited (GB) | 2008-07-23 | — | — | EP | claimed |
| WO-2008056151-A1 | TOPICAL FORMULATIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-05-15 | — | — | WO | claimed |
| WO-2007054693-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | HELPERBY THERAPEUTICS LIMITED (GB) | 2007-05-18 | — | — | WO | claimed |
| EP-0966466-B1 | PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RES INST CHEM TECH (KR) | 2002-07-03 | — | — | EP | claimed |
| US-6140033-A | SUPPORT WITH SILVER HALIDE EMULSIONS WITH COUPLERS | EASTMAN KODAK COMPANY (US) | 2000-10-31 | — | — | US | claimed |
| EP-1014185-A1 | Photographic element, pyrazolazole coupler, method for it's preparation and an azomethine dye | EASTMAN KODAK COMPANY (US) | 2000-06-28 | — | — | EP | claimed |
| CN-1258021-A | Photographic material | EASTMAN KODAK CO (US) | 2000-06-28 | — | — | CN | claimed |
| US-6011044-A | ANTIULCER AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-04 | — | — | US | claimed |
| EP-0966466-A1 | PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-12-29 | — | — | EP | claimed |
| WO-1999009029-A1 | PYRROLO[3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-02-25 | — | — | WO | claimed |