Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 7/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzodiazepine SCHEMBL27622539 | 0.88 | ALPI (0.36) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Benzodiazepine SCHEMBL27880113 | 0.85 | P2RX4 (0.34) | IDO1TDO2MAPT | |
| Benzodiazepine SCHEMBL28356183 | 0.83 | P2RX4 (0.32) | — | |
| Benzodiazepine SCHEMBL14740757 | 0.83 | MAPT (0.35) | POLBTDP1LMNAMAPTTSHR | |
| Benzodiazepine SCHEMBL29040975 | 0.82 | GAA (0.32) | KDM4ELMNAMAPTTSHR | |
| Benzodiazepine SCHEMBL1574261 | 0.81 | MAPT (0.36) | LMNAMAPTTSHR | |
| Benzodiazepine SCHEMBL29151800 | 0.80 | MAPT (0.35) | MAPT | |
| Benzodiazepine SCHEMBL28096295 | 0.80 | GAA (0.38) | MAPT | |
| Benzodiazepine SCHEMBL22578992 | 0.79 | MAPT (0.33) | KMT2AKDM4EMEN1MAPT | |
| Benzodiazepine SCHEMBL27786695 | 0.78 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143285-A1 | TARGET PROTEIN AND TARGET GENE FOR DRUG DISCOVERY AND SCREENING METHOD | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |