Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840619 | 0.81 | AGTR1 (0.46) | MMP8 | |
| SCHEMBL841345 | 0.81 | AGTR1 (0.45) | MMP8 | |
| SCHEMBL840227 | 0.78 | MMP8 (0.41) | MMP8MME | |
| SCHEMBL4554039 | 0.78 | AGTR1 (0.36) | — | |
| SCHEMBL840869 | 0.77 | AGTR1 (0.52) | MMP8 | |
| SCHEMBL839955 | 0.76 | MMP8 (0.43) | MMP8MME | |
| SCHEMBL841032 | 0.76 | MMP8 (0.44) | MMP8MME | |
| SCHEMBL839449 | 0.75 | AGTR1 (0.49) | MMP8 | |
| SCHEMBL839448 | 0.75 | AGTR1 (0.49) | MMP8 | |
| SCHEMBL839972 | 0.74 | AGTR1 (0.49) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132187-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008097459-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2008-08-14 | — | — | WO | disclosed |