⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592828 | 0.81 | — | — | |
| SCHEMBL3504687 | 0.80 | HDAC3 (0.53) | — | |
| SCHEMBL148962 | 0.79 | — | — | |
| SCHEMBL6970218 | 0.79 | — | — | |
| SCHEMBL28503636 | 0.79 | — | — | |
| SCHEMBL12124477 | 0.79 | ALDH1A1 (0.55) | — | |
| SCHEMBL19691137 | 0.79 | ALDH1A1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL10707489 | 0.78 | HDAC3 (0.52) | — | |
| SCHEMBL21585660 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL9331076 | 0.77 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176458-A1 | DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND | 石原産業株式会社 | 2023-09-21 | — | — | WO | claimed |
| CN-113968852-B | Thiazole hydrazide derivative and preparation method and application thereof | 同济大学 | 2023-08-15 | — | — | CN | claimed |
| CN-113461634-B | Thiazole hydrazide compound and preparation method and application thereof | 贵州大学 | 2023-07-04 | — | — | CN | claimed |
| CN-111875559-B | Thiazole hydrazide derivatives and application thereof as agricultural bactericide | 南京农业大学 | 2022-11-22 | — | — | CN | claimed |
| CN-113968852-A | Thiazole hydrazide derivative and preparation method and application thereof | 同济大学 | 2022-01-25 | — | — | CN | claimed |
| CN-113461634-A | Thiazole hydrazide compounds and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | claimed |
| CN-111875559-A | Thiazole hydrazide derivatives and application thereof as agricultural bactericide | 南京农业大学 | 2020-11-03 | — | — | CN | claimed |
| CN-104829608-B | A kind of cumarin thiazole indolone type compound and its preparation method and purposes | 吉首大学 | 2017-06-30 | — | — | CN | claimed |
| CN-104817552-B | (E) (base of cumarin 3) the hydrazide kind compound preparation method of thiazole 2 of N ' aryl methylenes 4 and purposes | 吉首大学 | 2017-06-27 | — | — | CN | claimed |
| EP-3836899-B1 | CHEMOTHERAPEUTIC PHARMACEUTICAL SUSPENSION FOR ORAL DOSAGE | ONCOSOL LTD (GB) | 2026-05-27 | — | — | EP | disclosed |
| EP-4628491-A1 | SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF NEUROKININ-3 RECEPTOR ANTAGONISTS | Química Sintética, S.A. (ES) | 2025-10-08 | — | — | EP | disclosed |
| CN-119591555-A | N' -aryl-4- [5- (trifluoromethyl) -1,2, 4-oxadiazole-3-yl ] benzoyl hydrazine compound and preparation and application thereof | 河北大学 | 2025-03-11 | — | — | CN | disclosed |
| US-20240374516-A1 | READY TO USE ORAL PHARMACEUTICAL SUSPENSION OF DASATINIB | ONCOSOL LIMITED (GB) | 2024-11-14 | — | — | US | disclosed |
| US-12083222-B2 | Chemotherapeutic pharmaceutical suspension for oral dosage | ONCOSOL LIMITED (GB) | 2024-09-10 | — | — | US | disclosed |
| US-20100151064-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | TECHNISCHE UNIVERSITAT DARMSTADT (DE) | 2010-06-17 | — | — | US | disclosed |
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | disclosed |
| EP-1918286-A1 | Thiazolhydrazides for treatment of neurodegenerative diseases | MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1918286-A1 | Thiazolhydrazides for treatment of neurodegenerative diseases | MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1918286-A1 | Thiazolhydrazides for treatment of neurodegenerative diseases | MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-07 | — | — | EP | disclosed |