SCHEMBL8592828

SCHEMBL8592828

O=C(NO)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970218 0.81
SCHEMBL148962 0.81
SCHEMBL455410 0.81
SCHEMBL28503636 0.81
SCHEMBL175249 0.77 ALDH1A1 (0.67)
SCHEMBL28027939 0.77 ALDH1A1 (0.67)
SCHEMBL19691137 0.76 ALDH1A1 (0.55)
SCHEMBL20712728 0.76 HSPA9 (0.60)
SCHEMBL1665911 0.76 ALDH1A1 (0.50)
SCHEMBL12124477 0.76 ALDH1A1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056785-A1 GAS-STORING MATERIAL INCLUDING METAL/ORGANIC FRAMEWORK BONDED BY HYDROXAMIC ACID RIKKYO EDUCATIONAL CORPORATION (JP) 2023-02-23 US disclosed
WO-2011145035-A1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) 2011-11-24 WO disclosed
EP-0639574-B1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD (KR) 1998-06-10 EP disclosed
EP-0371950-B1 Substituted thiazoles and their use as fungicides MONSANTO CO (US) 1995-01-11 EP disclosed
EP-0296673-B1 Thiazole derivatives SHELL INT RESEARCH (NL) 1994-03-09 EP disclosed
US-5045554-A Fluoro compounds, rice sheath blight, Basidiomycetes type fungus MONSANTO COMPANY (US) 1991-09-03 US disclosed
EP-0371950-A2 Substituted thiazoles and their use as fungicides Monsanto Company (US) 1990-06-06 EP disclosed
US-4897407-A PROTECTING PLANTS FROM FUNGAL DISEASES UNIROYAL CHEMICAL LIMITED (GB) 1990-01-30 US disclosed
US-4897407-A PROTECTING PLANTS FROM FUNGAL DISEASES UNIROYAL CHEMICAL LIMITED (GB) 1990-01-30 US disclosed
US-4767774-A Synergistic fungicidal composition employing substituted carboxamidothiazoles and imidazoles UNIROYAL CHEMICAL LIMITED (GB) 1988-08-30 US disclosed
US-4767774-A Synergistic fungicidal composition employing substituted carboxamidothiazoles and imidazoles UNIROYAL CHEMICAL LIMITED (GB) 1988-08-30 US disclosed
US-4767774-A Synergistic fungicidal composition employing substituted carboxamidothiazoles and imidazoles UNIROYAL CHEMICAL LIMITED (GB) 1988-08-30 US disclosed
EP-0209234-A2 Synergistic fungicidal composition UNIROYAL LIMITED (GB) 1987-01-21 EP disclosed
EP-0209234-A2 Synergistic fungicidal composition UNIROYAL LIMITED (GB) 1987-01-21 EP disclosed