⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908427 | 0.97 | — | — | |
| SCHEMBL4239769 | 0.79 | — | — | |
| SCHEMBL2846020 | 0.77 | — | — | |
| SCHEMBL16500034 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL11237346 | 0.69 | BHMT (0.36) | — | |
| SCHEMBL4555726 | 0.67 | — | — | |
| SCHEMBL15409111 | 0.65 | — | — | |
| SCHEMBL5533408 | 0.65 | — | — | |
| SCHEMBL22334183 | 0.65 | — | — | |
| SCHEMBL11281057 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120905-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR TREATING METABOLIC DISORDERS AND DIABETES | BELLUS Health (International) Limited (CH) | 2009-11-25 | — | — | EP | disclosed |
| EP-1968561-A2 | TREATMENT OF RENAL DISORDERS, DIABETIC NEPHROPATHY AND DYSLIPIDEMIAS | Neurochem (International) Limited (CH) | 2008-09-17 | — | — | EP | disclosed |
| WO-2008078176-A1 | METHODS, COMPOUNDS, AND COMPOSITIONS FOR TREATING METABOLIC DISORDERS AND DIABETES | BELLUS HEALTH (INTERNATIONAL) LIMITED (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-1885350-A2 | FORMULATIONS AND METHODS FOR TREATING AMYLOIDOSIS | Neurochem (International) Limited (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2007125385-A2 | TREATMENT OF RENAL DISORDERS, DIABETIC NEPHOPATHY AND DYSLIPIDEMIAS | NEUROCHEM (INTERNATIONAL) LIMITED (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007004072-A2 | FORMULATIONS AND METHODS FOR TREATING AMYLOIDOSIS | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-11 | — | — | WO | disclosed |