SCHEMBL4554161

SCHEMBL4554161

COc1ccc(CN(CCN)Cc2ccc(OC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.57
MAOB P27338 3/20 0.52
AOC3 Q16853 2/20 0.50
APLNR P35414 1/20 0.49
IDO1 P14902 3/20 0.47
AGXT P21549 2/20 0.47
PYCR1 P32322 1/20 0.46
SLC6A4 P31645 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11453792 0.91 TAAR1 (0.52) TAAR1MAOBAOC3APLNR
SCHEMBL12049800 0.83 APLNR (0.59) TAAR1AOC3APLNRIDO1AGXT
SCHEMBL5270803 0.83 APLNR (0.59) TAAR1AOC3APLNRIDO1AGXT
SCHEMBL18553360 0.83 TAAR1 (0.55) TAAR1MAOBAOC3APLNRIDO1
SCHEMBL17312007 0.83 CARM1 (0.61) TAAR1MAOBAOC3APLNRPYCR1
SCHEMBL4914707 0.83 CHRM2 (0.53) TAAR1LMNAALDH1A1HTT
SCHEMBL10039133 0.81 CALM1 (0.62) AOC3APLNRIDO1PYCR1SLC6A4
SCHEMBL8542070 0.81 TSHR (0.53) TAAR1AOC3ALDH1A1
SCHEMBL2070412 0.81 MEN1 (0.53) TAAR1MAOBLMNAMAPTALDH1A1
SCHEMBL4919382 0.81 CHRM2 (0.54) TAAR1LMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101168601-B Crosslinkers for improving stability of polyurethane foams AIR PROD & CHEM 2013-03-06 CN disclosed
EP-2114899-A2 CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES Firmenich S.A. (CH) 2009-11-11 EP disclosed
WO-2008093272-A2 CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES FIRMENICH SA (CH) 2008-08-07 WO disclosed
EP-1765833-A2 NEWS SALTS IN THE PREPARATION OF CEPHALOSPORIN ANTIBIOTICS Orchid Chemicals and Pharmaceuticals Limited (IN) 2007-03-28 EP disclosed
WO-2006006040-A2 NEWS DIAMINE SALTS OF CEPHALOSPORIN ANTIBIOTICS AND THEIR PREPARATION ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) 2006-01-19 WO disclosed