SCHEMBL455439

SCHEMBL455439

Cc1ccc(NC(=O)O)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
POLB P06746 2/20 0.67
NPC1 O15118 4/20 0.64
RAB9A P51151 3/20 0.64
MAPT P10636 3/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
NMT1 P30419 1/20 0.61
KIF11 P52732 1/20 0.59
TGM2 P21980 1/20 0.59
KDM4E B2RXH2 1/20 0.59
DDAH1 O94760 1/20 0.53
ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL11790965 0.97 TDP1 (0.67) TDP1POLBNPC1RAB9AMAPT
SCHEMBL10778839 0.89 SMN1; SMN2 (0.52) TDP1POLBNPC1RAB9AMAPT
Hydrochloric Acid SCHEMBL11405284 0.86 SMN1; SMN2 (0.50) TDP1POLBNPC1RAB9AMAPT
Toluene SCHEMBL28333295 0.85 NAPRT (0.60) TDP1POLBNPC1RAB9AMAPT
Toluene SCHEMBL28033107 0.85 NAPRT (0.60) TDP1POLBNPC1RAB9AMAPT
SCHEMBL6850999 0.84 KDM4E (0.79) TDP1POLBNPC1RAB9AMAPT
SCHEMBL1275920 0.84 ALDH1A1 (0.70) TDP1POLBNPC1RAB9AMAPT
SCHEMBL9613267 0.83 NPC1 (0.64) TDP1POLBNPC1RAB9AMAPT
SCHEMBL61417 0.82 TDP1 (1.00) TDP1POLBNPC1RAB9AMAPT
SCHEMBL4899667 0.82 TDP1 (0.74) TDP1POLBNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462429-A Method for synthesizing amino-methyl-phenyl methyl carbamate compound from p-toluidine 河北工业大学 2025-02-18 CN claimed
EP-3577149-B1 METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-02-09 EP claimed
CN-109152363-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-10-15 CN claimed
EP-3500611-B1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-08-11 EP claimed
EP-3461931-B1 COMPOSITIONS OF VAPOUR PHASE CORROSION INHIBITORS AND THEIR USE AND METHOD FOR PREPARING THEM EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2020-03-25 EP claimed
EP-2908843-B1 TREATING CANCER AGENCY SCIENCE TECH & RES (SG) 2019-09-04 EP claimed
CN-109642010-A The synthetic method of poly- Oxazolidinone compound 科思创德国股份有限公司 2019-04-16 CN claimed
EP-3461931-A1 COMPOSITIONS OF VAPOUR PHASE CORROSION INHIBITORS AND THEIR USE AND METHOD FOR PREPARING THEM EXCOR Korrosionsforschung GmbH (DE) 2019-04-03 EP claimed
EP-3256508-B1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2019-03-27 EP claimed
CN-104792891-B A kind of detection method of R configuration Rivaroxaban intermediate 成都百裕制药股份有限公司 2017-03-01 CN claimed
EP-0809714-A1 MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES HENKEL CORPORATION (US) 1997-12-03 EP claimed
EP-0550879-B1 Process for coating cellulosic membranes AKZO NOBEL NV (NL) 1997-03-12 EP claimed
WO-1996025525-A1 MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES HENKEL CORPORATION (US) 1996-08-22 WO claimed
US-5360636-A Method for coating cellulosic membranes AKZO NV (NL) 1994-11-01 US claimed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
EP-0509795-A2 Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1992-10-21 EP claimed
US-5118678-A Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-06-02 US claimed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP claimed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US claimed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US claimed