Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.51 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770646 | 0.99 | ADRB2 (0.52) | ADRB2ADRB1DRD3 | |
| SCHEMBL4554541 | 0.79 | ADRB2 (0.59) | ADRB2ADRB1DRD3 | |
| SCHEMBL3770650 | 0.78 | ADRB2 (0.61) | ADRB2ADRB1DRD3 | |
| Hydrochloric Acid SCHEMBL4773682 | 0.78 | ADRB2 (0.49) | ADRB2ADRB1 | |
| SCHEMBL3685863 | 0.75 | ADRB2 (0.40) | ADRB2ADRB1DRD3 | |
| SCHEMBL4554542 | 0.74 | ADRB2 (0.50) | ADRB2ADRB1DRD3 | |
| SCHEMBL2815404 | 0.73 | ADRB2 (0.54) | ADRB2ADRB1DRD3 | |
| SCHEMBL3770653 | 0.73 | ADRB2 (0.52) | ADRB2ADRB1DRD3 | |
| SCHEMBL1683037 | 0.73 | ADRB2 (0.47) | ADRB2ADRB1DRD3 | |
| SCHEMBL2817307 | 0.72 | ADRB2 (0.56) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075026-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |