Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 20/20 | 0.59 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770650 | 0.99 | ADRB2 (0.61) | ADRB2ADRB1DRD3 | |
| SCHEMBL1683040 | 0.79 | ADRB2 (0.50) | ADRB2ADRB1DRD3 | |
| SCHEMBL4554540 | 0.79 | ADRB2 (0.51) | ADRB2ADRB1DRD3 | |
| SCHEMBL3770646 | 0.78 | ADRB2 (0.52) | ADRB2ADRB1DRD3 | |
| Hydrochloric Acid SCHEMBL4773688 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1DRD3 | |
| SCHEMBL3685866 | 0.75 | ADRB2 (0.48) | ADRB2ADRB1DRD3 | |
| SCHEMBL2208618 | 0.73 | ADRB2 (0.54) | ADRB2ADRB1DRD3 | |
| SCHEMBL2215025 | 0.73 | ADRB2 (0.55) | ADRB2ADRB1DRD3 | |
| SCHEMBL2212515 | 0.73 | ADRB2 (0.55) | ADRB2ADRB1DRD3 | |
| SCHEMBL2212359 | 0.73 | ADRB2 (0.55) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008075026-A1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |