Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556658 | 0.90 | CA12 (0.58) | CA12CA9HTTHCRTR1ALOX15 | |
| SCHEMBL4555518 | 0.87 | CA12 (0.45) | CA12CA9HTTHCRTR1SMN1; SMN2 | |
| SCHEMBL1664524 | 0.79 | CA12 (0.56) | CA12CA9HTTPLAUSMN1; SMN2 | |
| SCHEMBL4556438 | 0.77 | KMT2A (0.60) | HTTPLAUSMN1; SMN2MEN1MAPT | |
| SCHEMBL6073367 | 0.77 | CA12 (0.72) | CA12CA9HTTSMN1; SMN2MEN1 | |
| SCHEMBL8752463 | 0.74 | CA12 (1.00) | CA12CA9HTTALOX15SMN1; SMN2 | |
| SCHEMBL10947961 | 0.73 | CA12 (0.76) | CA12CA9HTTALOX15SMN1; SMN2 | |
| SCHEMBL4556569 | 0.72 | PTGES (0.47) | HCRTR1MEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL3046360 | 0.72 | CA12 (0.78) | CA12CA9HTTSMN1; SMN2MEN1 | |
| SCHEMBL28930344 | 0.71 | IL1RN (0.64) | CA12CA9HTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541074-B2 | Optical film and optical compensatory film, polarizing plate and liquid crystal display using same | FUJIFILM CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20070190268-A1 | Optical film and optical compensatory film, polarizing plate and liquid crystal display using same | FUJI PHOTO FILM CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |