Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199919 | 0.86 | — | — | |
| SCHEMBL239043 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5751357 | 0.78 | — | — | |
| SCHEMBL7767135 | 0.76 | CRHBP (0.42) | CRHBPCRHR2MALT1TSHR | |
| SCHEMBL16014041 | 0.74 | CRHBP (0.41) | CRHBPCRHR2TSHR | |
| Hydrochloric Acid SCHEMBL11254712 | 0.73 | CRHBP (0.40) | CRHBPCRHR2TSHR | |
| SCHEMBL8465591 | 0.71 | CRHBP (0.40) | CRHBPCRHR2TSHR | |
| SCHEMBL3475820 | 0.71 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL817805 | 0.70 | CRHBP (0.44) | CRHBPCRHR2TSHR | |
| SCHEMBL9412076 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013211-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | Novartis AG (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |