⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323511 | 0.93 | — | — | |
| SCHEMBL28158852 | 0.68 | — | — | |
| SCHEMBL9614870 | 0.67 | — | — | |
| SCHEMBL5983448 | 0.63 | — | — | |
| SCHEMBL11228217 | 0.61 | — | — | |
| SCHEMBL8719021 | 0.61 | — | — | |
| SCHEMBL10842659 | 0.59 | — | — | |
| SCHEMBL8709772 | 0.57 | — | — | |
| SCHEMBL4552680 | 0.56 | — | — | |
| SCHEMBL10078195 | 0.56 | CHEK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| EP-2126053-A2 | APOCRINE CELL LINE | Unilever PLC (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008116713-A2 | APOCRINE CELL LINE | UNILEVER PLC (GB) | 2008-10-02 | — | — | WO | disclosed |
| EP-1414467-B1 | TOPICAL TREATMENT FOR MASTALGIA | SCHMIDT ALFRED (DE) | 2006-04-26 | — | — | EP | disclosed |
| EP-1414467-A2 | TOPICAL TREATMENT FOR MASTALGIA | Schmidt, Alfred (DE) | 2004-05-06 | — | — | EP | disclosed |
| CN-1128148-C | Process for the synthesis of (1H)-benzo [C] quinolizin-3-ones derivatives | APPLIED RESEARCH SYSTEMS (AN) | 2003-11-19 | — | — | CN | disclosed |
| WO-2002036129-A2 | TOPICAL TREATMENT OF MASTALGIA WITH AROMETESE INHIBITORS SUCH AS ANDROSTENDIONE | SCHMIDT ALFRED (DE) | 2002-05-10 | — | — | WO | disclosed |
| CN-1311788-A | Process for the synthesis of (1H)-benzo [C] quinolizin-3-ones derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2001-09-05 | — | — | CN | disclosed |
| EP-1115724-A1 | QUINOLIZINONES AS INTEGRIN INHIBITORS | Shire Biochem Inc. (CA) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017197-A1 | QUINOLIZINONES AS INTEGRIN INHIBITORS | BIOCHEM PHARMA INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998025930-A2 | USE OF BI- AND TRICYCLIC PYRIDONE DERIVATIVES AGAINST ALZHEIMER'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-18 | — | — | WO | disclosed |