SCHEMBL9614870

SCHEMBL9614870

O=C1C=CC2=CC=CCN12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17894038 0.71
SCHEMBL2222528 0.70
SCHEMBL27510089 0.68
SCHEMBL15574709 0.68
SCHEMBL24080664 0.68 MGLL (0.34)
SCHEMBL4879869 0.68
SCHEMBL4554902 0.67
SCHEMBL29969013 0.66
SCHEMBL19210810 0.66
SCHEMBL10077299 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4577024-A PHOTOTHERMOGRAPHY, LASER RECORDING EASTMAN KODAK COMPANY (US) 1986-03-18 US claimed
JP-4108790-A None JP disclosed
US-20250257035-A1 1,4-Substituted Piperidine Derivatives CEPHALON LLC 2025-08-14 US disclosed
US-12098130-B2 1,4-substituted piperidine derivatives 89BIO LTD (IL) 2024-09-24 US disclosed
US-20240166625-A1 Substituted 4-Benzyl And 4-Benzoyl Piperidine Derivates CEPHALON LLC 2024-05-23 US disclosed
US-11878966-B2 Substituted 4-benzyl and 4-benzoyl piperidine derivates 89BIO LTD (IL) 2024-01-23 US disclosed
US-20230391723-A1 1,4-Substituted Piperidine Derivatives CEPHALON LLC 2023-12-07 US disclosed
US-11702388-B2 1,4-substituted piperidine derivatives 89BIO LTD (IL) 2023-07-18 US disclosed
US-20210230116-A1 1,4-Substituted Piperidine Derivatives CEPHALON LLC 2021-07-29 US disclosed
CN-107847765-B 1, 4-substituted piperidine derivatives 89生物有限公司 2021-05-04 CN disclosed
US-20180179159-A1 1,4-SUBSTITUTED PIPERIDINE DERIVATIVES CEPHALON LLC 2018-06-28 US disclosed
EP-3310441-A1 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES Cephalon, Inc. (US) 2018-04-25 EP disclosed
EP-3310773-A1 SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES Cephalon, Inc. (US) 2018-04-25 EP disclosed
US-9902696-B2 1,4-substituted piperidine derivatives CEPHALON, INC. (US) 2018-02-27 US disclosed
WO-2016205633-A1 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES CEPHALON, INC. (US) 2016-12-22 WO disclosed
WO-2016205590-A1 SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES CEPHALON, INC. (US) 2016-12-22 WO disclosed
US-20160368874-A1 1,4-SUBSTITUTED PIPERIDINE DERIVATIVES CEPHALON LLC 2016-12-22 US disclosed
EP-0480939-A1 HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. UPJOHN CO (US) 1992-04-22 EP disclosed
JP-H04108790-A THIENO (2,3-B) INDOLIZINE DERIVATIVE KISSEI PHARMACEUT CO LTD 1992-04-09 JP disclosed
US-4577024-A PHOTOTHERMOGRAPHY, LASER RECORDING EASTMAN KODAK COMPANY (US) 1986-03-18 US disclosed