Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020064 | 0.78 | PRCP (0.53) | KDM4ETSHRALDH1A1 | |
| SCHEMBL15355400 | 0.78 | PRCP (0.53) | KDM4ETSHRALDH1A1 | |
| SCHEMBL5682329 | 0.76 | MAOA (0.64) | DRD2DRD1SLC6A9KDM1AKDM4E | |
| SCHEMBL21470621 | 0.76 | MAOA (0.64) | DRD2DRD1SLC6A9KDM1AKDM4E | |
| SCHEMBL30199335 | 0.76 | MAOA (0.64) | DRD2DRD1SLC6A9KDM1AKDM4E | |
| Bromide SCHEMBL5680654 | 0.74 | MAOA (0.65) | DRD2DRD1SLC6A9KDM1AKDM4E | |
| SCHEMBL27552616 | 0.74 | DRD2 (0.49) | DRD2DRD1CA1CA2CA7 | |
| SCHEMBL29731083 | 0.73 | TSHR (0.64) | DRD2DRD1CA1CA2CA7 | |
| Bromide SCHEMBL5680650 | 0.73 | MAOA (0.60) | DRD2DRD1SLC6A9KDM1AKDM4E | |
| SCHEMBL32684608 | 0.73 | PRCP (0.60) | DRD2DRD1SLC6A9KDM1AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | disclosed |