Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamate SCHEMBL4554947 | 0.85 | HRH2 (0.45) | HTR3AMAPTCNR1CNR2GSK3B | |
| SCHEMBL2817707 | 0.82 | ALDH1A1 (0.50) | HTR3AMAPTCNR1CNR2GSK3B | |
| SCHEMBL25403772 | 0.78 | CNR1 (0.50) | HTR3ALMNAMAPTPOLBNPSR1 | |
| SCHEMBL31083818 | 0.78 | CNR1 (0.50) | HTR3ALMNAMAPTPOLBNPSR1 | |
| SCHEMBL30564140 | 0.78 | SMN1; SMN2 (0.56) | HTR3ALMNAMAPTPOLBNPSR1 | |
| SCHEMBL25404249 | 0.75 | IDO1 (0.58) | HTR3ACNR1CNR2ICMTIDO1 | |
| SCHEMBL4602725 | 0.73 | GSK3B (0.47) | NPSR1CNR1CNR2GSK3BICMT | |
| SCHEMBL4602721 | 0.72 | GSK3B (0.47) | NPSR1CNR1CNR2GSK3BICMT | |
| SCHEMBL2814624 | 0.71 | ALDH1A1 (0.61) | LMNAMAPTPOLBGSK3BSMN1; SMN2 | |
| SCHEMBL20379523 | 0.69 | SCN9A (0.46) | HTR3ALMNAMAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |