Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817707 | 0.93 | ALDH1A1 (0.50) | HRH2ALDH1A1IDO1CNR1GSK3B | |
| SCHEMBL25403772 | 0.86 | CNR1 (0.50) | HRH2ALDH1A1IDO1CNR1CNR2 | |
| SCHEMBL31083818 | 0.86 | CNR1 (0.50) | HRH2ALDH1A1IDO1CNR1CNR2 | |
| SCHEMBL4554948 | 0.85 | HTR3A (0.45) | IDO1CNR1GSK3BCNR2MAPT | |
| SCHEMBL4494230 | 0.77 | CNR2 (0.61) | HRH2CNR1CNR2KDM4CHTR3A | |
| SCHEMBL30564140 | 0.76 | SMN1; SMN2 (0.56) | ALDH1A1IDO1CNR1CNR2MAPT | |
| SCHEMBL13537206 | 0.76 | CNR2 (0.52) | ALDH1A1IDO1CNR1CNR2MAPT | |
| SCHEMBL12485447 | 0.76 | KDM4E (0.54) | ALDH1A1IDO1CNR1CNR2KDM4C | |
| SCHEMBL2816604 | 0.75 | CNR2 (0.51) | IDO1CNR1GSK3BCNR2KDM4C | |
| SCHEMBL6042188 | 0.75 | CNR2 (0.70) | ALDH1A1CNR1CNR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |