Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010742 | 0.88 | EPHX2 (0.66) | EPHX2EPHX1 | |
| SCHEMBL14072843 | 0.82 | EPHX2 (0.74) | EPHX2EPHX1 | |
| SCHEMBL13768765 | 0.82 | EPHX2 (0.72) | EPHX2EPHX1 | |
| SCHEMBL5000909 | 0.81 | EPHX2 (0.74) | EPHX2EPHX1 | |
| SCHEMBL1425023 | 0.81 | EPHX2 (0.74) | EPHX2EPHX1RECQL | |
| SCHEMBL4011008 | 0.81 | L3MBTL1 (0.63) | EPHX2EPHX1 | |
| SCHEMBL4997641 | 0.80 | EPHX2 (0.73) | EPHX2EPHX1 | |
| SCHEMBL4010386 | 0.80 | EPHX2 (0.75) | EPHX2EPHX1 | |
| SCHEMBL17327832 | 0.79 | EPHX2 (0.74) | EPHX2 | |
| SCHEMBL4109475 | 0.79 | EPHX2 (0.67) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132176-A1 | 4-PIPERIDINYLUREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Arete Therapeutics, Inc. (US) | 2009-12-16 | — | — | EP | claimed |
| WO-2008112022-A1 | 4 -PI PERIDINYLUREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | ARETE THERAPEUTICS, INC. (US) | 2008-09-18 | — | — | WO | claimed |