Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12702894 | 0.86 | GAA (0.33) | GAA | |
| SCHEMBL307153 | 0.85 | P2RX7 (0.42) | GAA | |
| SCHEMBL307154 | 0.85 | P2RX7 (0.42) | GAA | |
| SCHEMBL305878 | 0.80 | P2RX7 (0.33) | — | |
| SCHEMBL305879 | 0.80 | P2RX7 (0.33) | — | |
| SCHEMBL307042 | 0.67 | MAPT (0.33) | — | |
| SCHEMBL12703131 | 0.66 | ALDH1A1 (0.40) | GAA | |
| SCHEMBL305691 | 0.65 | P2RX7 (0.43) | GAA | |
| SCHEMBL12702939 | 0.65 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL305725 | 0.65 | P2RX7 (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124562-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008112205-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |