Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555541 | 0.87 | MAPT (0.49) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL4555539 | 0.84 | MAPT (0.50) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL2813712 | 0.78 | KMT2A (0.67) | MAPTTP53ALDH1A1HTTLMNA | |
| SCHEMBL2816819 | 0.78 | MEN1 (0.63) | MAPTTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL4448114 | 0.77 | LMNA (0.48) | MAPTTP53ALDH1A1HTTLMNA | |
| SCHEMBL2816590 | 0.76 | LMNA (0.62) | MAPTGAAALDH1A1LMNAPOLB | |
| SCHEMBL2815071 | 0.76 | MEN1 (0.54) | MAPTTP53ALDH1A1KDM4ENPC1 | |
| SCHEMBL2815527 | 0.76 | MEN1 (0.56) | MAPTTP53ALDH1A1POLBNPC1 | |
| SCHEMBL2819556 | 0.76 | MEN1 (0.56) | MAPTTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL2815122 | 0.76 | KMT2A (0.57) | MAPTTP53ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |