Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555539 | 0.90 | MAPT (0.50) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL4555540 | 0.87 | MAPT (0.50) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL2814428 | 0.80 | KMT2A (0.60) | MAPTTP53ALDH1A1POLBMEN1 | |
| SCHEMBL4448117 | 0.77 | LMNA (0.46) | MAPTTP53ALDH1A1KDM4EHTT | |
| SCHEMBL4554530 | 0.76 | MEN1 (0.48) | MAPTTP53ALDH1A1KDM4ELMNA | |
| SCHEMBL4554814 | 0.74 | MEN1 (0.50) | MAPTTP53KDM4EHTTPOLB | |
| SCHEMBL4556337 | 0.74 | NPC1 (0.56) | TP53ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL4556271 | 0.74 | PKM (0.46) | MAPTTP53ALDH1A1KDM4EHTT | |
| SCHEMBL14955540 | 0.74 | POLB (0.53) | MAPTTP53GAAALDH1A1KDM4E | |
| SCHEMBL4446512 | 0.73 | PKM (0.51) | MAPTTP53ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |